Page 1 of 9 Title: Flow Cytometric Testing for Kappa and Lambda light chains Sponsored and reviewed by ICCS Quality and Standar
![Ultrasensitive automated RNA in situ hybridization for kappa and lambda light chain mRNA detects B-cell clonality in tissue biopsies with performance comparable or superior to flow cytometry | Modern Pathology Ultrasensitive automated RNA in situ hybridization for kappa and lambda light chain mRNA detects B-cell clonality in tissue biopsies with performance comparable or superior to flow cytometry | Modern Pathology](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fmodpathol.2017.142/MediaObjects/41379_2018_Article_BFmodpathol2017142_Fig2_HTML.jpg)
Ultrasensitive automated RNA in situ hybridization for kappa and lambda light chain mRNA detects B-cell clonality in tissue biopsies with performance comparable or superior to flow cytometry | Modern Pathology
![Biclonal plasma cell myeloma with the simultaneous appearance of both secretory lambda and nonsecretory kappa monoclonal light chains Biclonal plasma cell myeloma with the simultaneous appearance of both secretory lambda and nonsecretory kappa monoclonal light chains](https://www.degruyter.com/document/doi/10.1515/cclm-2016-0364/asset/graphic/j_cclm-2016-0364_fig_002.jpg)
Biclonal plasma cell myeloma with the simultaneous appearance of both secretory lambda and nonsecretory kappa monoclonal light chains
![A Novel Multiparametric Approach for Analysis of Cytoplasmic Immunoglobulin Light Chains by Flow Cytometry | Modern Pathology A Novel Multiparametric Approach for Analysis of Cytoplasmic Immunoglobulin Light Chains by Flow Cytometry | Modern Pathology](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fmodpathol.3880427/MediaObjects/41379_2001_Article_BF3880427_Fig1_HTML.jpg)
A Novel Multiparametric Approach for Analysis of Cytoplasmic Immunoglobulin Light Chains by Flow Cytometry | Modern Pathology
![Cureus | Secondary Plasma Cell Leukemia in a Recurrent Multiple Myeloma: Rare Case Scenario | Article Cureus | Secondary Plasma Cell Leukemia in a Recurrent Multiple Myeloma: Rare Case Scenario | Article](https://assets.cureus.com/uploads/figure/file/111136/lightbox_e452ddf0810f11ea8b803feb65fc6c9c-PCL-Fig-1-enhance.png)
Cureus | Secondary Plasma Cell Leukemia in a Recurrent Multiple Myeloma: Rare Case Scenario | Article
![Immunohistochemistry evidenced kappa immunoglobulin light chain (A)... | Download Scientific Diagram Immunohistochemistry evidenced kappa immunoglobulin light chain (A)... | Download Scientific Diagram](https://www.researchgate.net/publication/305712419/figure/fig3/AS:391504213364736@1470353286092/Immunohistochemistry-evidenced-kappa-immunoglobulin-light-chain-A-restriction-x400.png)
Immunohistochemistry evidenced kappa immunoglobulin light chain (A)... | Download Scientific Diagram
Arrows pointing at CD138-positive (kappa restricted) sheets of plasma... | Download Scientific Diagram
![A case of solitary plasmacytoma of bone showing co-expression of both immunoglobulin light chains | European Journal of Medical Research | Full Text A case of solitary plasmacytoma of bone showing co-expression of both immunoglobulin light chains | European Journal of Medical Research | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs40001-021-00621-8/MediaObjects/40001_2021_621_Fig3_HTML.jpg)
A case of solitary plasmacytoma of bone showing co-expression of both immunoglobulin light chains | European Journal of Medical Research | Full Text
![Lupus mastitis with predominant kappa-restricted plasma cell infiltration: report of a rare case | Surgical and Experimental Pathology | Full Text Lupus mastitis with predominant kappa-restricted plasma cell infiltration: report of a rare case | Surgical and Experimental Pathology | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs42047-020-00077-w/MediaObjects/42047_2020_77_Fig2_HTML.png)
Lupus mastitis with predominant kappa-restricted plasma cell infiltration: report of a rare case | Surgical and Experimental Pathology | Full Text
![Plasma cell myeloma expressing IgG heavy chain with co-expression of... | Download Scientific Diagram Plasma cell myeloma expressing IgG heavy chain with co-expression of... | Download Scientific Diagram](https://www.researchgate.net/publication/281513243/figure/fig4/AS:931509057896449@1599100474239/Plasma-cell-myeloma-expressing-IgG-heavy-chain-with-co-expression-of-kappa-and-lambda.png)
Plasma cell myeloma expressing IgG heavy chain with co-expression of... | Download Scientific Diagram
![Immunophenotypic and cytogenetic evolution patterns of the neoplastic plasma cells in multiple myeloma relapsed after stem cell transplant | SpringerLink Immunophenotypic and cytogenetic evolution patterns of the neoplastic plasma cells in multiple myeloma relapsed after stem cell transplant | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs12308-018-0330-6/MediaObjects/12308_2018_330_Fig1_HTML.png)
Immunophenotypic and cytogenetic evolution patterns of the neoplastic plasma cells in multiple myeloma relapsed after stem cell transplant | SpringerLink
![Biclonal plasma cell myeloma with the simultaneous appearance of both secretory lambda and nonsecretory kappa monoclonal light chains Biclonal plasma cell myeloma with the simultaneous appearance of both secretory lambda and nonsecretory kappa monoclonal light chains](https://www.degruyter.com/document/doi/10.1515/cclm-2016-0364/asset/graphic/j_cclm-2016-0364_fig_001.jpg)
Biclonal plasma cell myeloma with the simultaneous appearance of both secretory lambda and nonsecretory kappa monoclonal light chains
![Ultrasensitive automated RNA in situ hybridization for kappa and lambda light chain mRNA detects B-cell clonality in tissue biopsies with performance comparable or superior to flow cytometry | Modern Pathology Ultrasensitive automated RNA in situ hybridization for kappa and lambda light chain mRNA detects B-cell clonality in tissue biopsies with performance comparable or superior to flow cytometry | Modern Pathology](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fmodpathol.2017.142/MediaObjects/41379_2018_Article_BFmodpathol2017142_Fig1_HTML.jpg)
Ultrasensitive automated RNA in situ hybridization for kappa and lambda light chain mRNA detects B-cell clonality in tissue biopsies with performance comparable or superior to flow cytometry | Modern Pathology
![Quantification of clonal circulating plasma cells in newly diagnosed multiple myeloma: implications for redefining high-risk myeloma | Leukemia Quantification of clonal circulating plasma cells in newly diagnosed multiple myeloma: implications for redefining high-risk myeloma | Leukemia](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fleu.2014.98/MediaObjects/41375_2014_Article_BFleu201498_Fig1_HTML.jpg)
Quantification of clonal circulating plasma cells in newly diagnosed multiple myeloma: implications for redefining high-risk myeloma | Leukemia
![a) Immunohistochemistry shows plasma cells strongly positive for CD... | Download Scientific Diagram a) Immunohistochemistry shows plasma cells strongly positive for CD... | Download Scientific Diagram](https://www.researchgate.net/publication/292160985/figure/fig1/AS:363093361217536@1463579611125/a-Immunohistochemistry-shows-plasma-cells-strongly-positive-for-CD-38-b-with-no.png)
a) Immunohistochemistry shows plasma cells strongly positive for CD... | Download Scientific Diagram
![Plasmacytic or lymphoplasmacytic infiltrate in lymph nodes: Diagnostic approach and differential considerations Plasmacytic or lymphoplasmacytic infiltrate in lymph nodes: Diagnostic approach and differential considerations](https://ijpmonline.org/articles/2016/59/4/images/IndianJPatholMicrobiol_2016_59_4_446_191756_u8.jpg)
Plasmacytic or lymphoplasmacytic infiltrate in lymph nodes: Diagnostic approach and differential considerations
![Flow Cytometric Immunophenotypic Analysis in the Diagnosis and Prognostication of Plasma Cell Neoplasms - Wang - 2019 - Cytometry Part B: Clinical Cytometry - Wiley Online Library Flow Cytometric Immunophenotypic Analysis in the Diagnosis and Prognostication of Plasma Cell Neoplasms - Wang - 2019 - Cytometry Part B: Clinical Cytometry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/8ecec53e-73c1-4870-a06e-308e155b9cac/cytob21844-fig-0001-m.jpg)
Flow Cytometric Immunophenotypic Analysis in the Diagnosis and Prognostication of Plasma Cell Neoplasms - Wang - 2019 - Cytometry Part B: Clinical Cytometry - Wiley Online Library
![Kappa and lambda immunohistochemistry and in situ hybridization in the evaluation of atypical cutaneous lymphoid infiltrates - Hristov - 2020 - Journal of Cutaneous Pathology - Wiley Online Library Kappa and lambda immunohistochemistry and in situ hybridization in the evaluation of atypical cutaneous lymphoid infiltrates - Hristov - 2020 - Journal of Cutaneous Pathology - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/ec451350-c748-4112-a036-ef938dcc377c/cup13858-fig-0002-m.jpg)